4 research outputs found
The morphological evaluation of ipsilateral and contralateral vasa deferentia in a rat model of unilateral spermatic cord torsion
Aim Spermatic cord torsion is a surgical emergency that
requires early intervention to protect the effected testicle.
The literature review about this ischemic reperfusion (I/R)
injury reveals not only ipsilateral, but also contralateral
testicular and epididymal injuries in a broad fashion.
However, there is no data about vas deferens injury related
with this surgical emergency. The aim of the study is to
evaluate the morphological changes of the vas deferens due
to testicular I/R injury.
Materials and methods Eighteen Wistar-Albino rats were
allocated to three groups. Bilateral vasa deferentia of
control group (Gr C, n = 6) were harvested without any
surgical intervention. The torsion group was subjected to
2 h torsion and 2 h detorsion of the left testicle (Gr T,
n = 6) and the third group underwent sham operations (Gr
S, n = 6). Bilateral vasa deferentia of Gr T and S were
harvested after surgery. The either side of the vas deferens
was divided into three equal segments and these regions
(adjacent to urinary bladder, medial and adjacent to testicle)
were evaluated histopathologically.
Results The electron microscopic evaluation of bilateral
vasa deferentia of Gr T revealed different degrees of
degeneration on either side. The region adjacent to testicle
of the contralateral vas deferens was the most effected
segment when compared with the other segments.
Conclusion In the light of these findings, it can be said
that testicular I/R injury effects not only testis and epididymis,
but also the adjacent vas deferens. This effect seems
to be bilateral, like the testis and epididymis injury. Moreover,
it mostly seems to depend on the apoptotic processes